Stem cells genetics – and epigenetics – one cell at a time
The genetic processes and epigenetic modifications during cell differentiation are heterogeneous – i.e. neighbouring cells behave differently and insights based on cell populations don’t tell the real story. So you want to study expression of RNA and microRNAs on single cells but are looking for the right platform .
Join leading stem cell researchers and try the AmpliGrid system of the Advalytix product group of Beckman Coulter for simple, affordable and reliable molecular analysis of just single stem cells.
OUR SOLUTION
Many of our customers study stem cells – oncologists to find tumor stem cells, and developmental biologists to study ontogenesis; they have helped us to constantly refine and improve our workflows and applications to suit the needs of the stem cell community:
• Simple and cost effective integration with flow cytometry
• Open, cost effective single cell workflow
• Protocols for typical stem cell applications, such as Multiplex rt-PCR expression analysis of developmentally important genes
• A community of stem cell researchers to share experiences such as Laurie Jackson-Grusby at the Boston Children’s Hospital, and Andreas May/ Thomas Haaf at the Institute for Human Genetics, Mainz, Germany
USER STORIES
- Prof. Haaf uses AmpliGrid for multiplex RT-PCR expression analysis of developmentally important genes in individual mouse preimplantation embryos and blastomeres
- Karin Görner and Katharina Pachmann use AmpliCell and AmpliGrid as a new cell culture and PCR platform for analysis of tumor stem cells
- Dr. Laurie Jackson Grusby searches for brain tumor stem cells (GEN article)
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